Review on Functional Interrogation of Genes Driving Colorectal Cancer
by quines on Feb.08, 2010, under ChemSem 04, _Spring 2010
This week, for our regular Thursday seminar we had Assistant Professor Amanda Hummon from Notre Dame University. Her main topic was on cancer and proteomics, more specifically on colon cancer. Her presentation was interesting and she was able to present well. Her presentation was easy to follow and organized well enough so that the audience could remain attentive.
Hummon started with a brief overview of cancer and how cancer cells differ from normal cells. I learned about the six phenotypic differences between cancer and normal cells. Among these include increased, abhorrent proliferation; modification of equilibrium to prevent apoptosis; angiogenesis; and metastisis. Hummon continued her presentation continued as she described procedures and spectroscopic methods. I was able to learn more about spectral karyotyping and comparitive genomic hybridization. She then concluded her overview by stating her main goal which was elucidating the deregulated gene products that drive colorectal cancer.
It was interesting to see how her research progressed, and to learn about the new discoveries that she was able to find. We were able to see how some of the chromosomes were modified from the typical 46 to up to 58. I would say her whole presentation was very informative, despite not having as much chemistry content as we are used to seeing for seminar. Since she gave an easy to follow presentation, we were able to ask some thoughtful questions.
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